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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
P08727
USC-OGP 2-DE database
:
P08727
P08727
General information about the entry
View entry in simple text format
Entry name
K1C19_HUMAN
Primary accession number
P08727
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Keratin, type I cytoskeletal 19; AltName: Full=Cytokeratin-19; Short=CK-19; AltName: Full=Keratin-19; Short=K19;.
Gene name
Name=KRT19
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1185
:
pI=6.07; Mw=43048
SPOT OGP-1189
:
pI=5.12; Mw=42209
Cross-references
UniProtKB/Swiss-Prot
P08727; K1C19_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
K1C19_HUMAN
Primary accession number
P08727
Secondary accession number(s)
B2R874 Q5XG83 Q6NW33 Q7L5M9 Q96A53 Q96FV1 Q9BYF9 Q9P1Y4
Sequence was last modified on
November 2, 2010 (version 4)
Annotations were last modified on
March 15, 2017 (version 179)
Name and origin of the protein
Description
RecName: Full=Keratin, type I cytoskeletal 19; AltName: Full=Cytokeratin-19; Short=CK-19; AltName: Full=Keratin-19; Short=K19;
Gene name
Name=KRT19
Encoded on
Name=KRT19
Keywords
Coiled coil
;
Complete proteome
;
Direct protein sequencing
;
Host-virus interaction
;
Intermediate filament
;
Keratin
;
Methylation
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
J03607; AAA36044.1
; -; Genomic_DNA
EMBL
Y00503; CAA68556.1
; -; mRNA
EMBL
AF202321; AAF27048.1
; -; Genomic_DNA
EMBL
AK313261; BAG36071.1
; -; mRNA
EMBL
AC019349; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
BC002539; AAH02539.3
; -; mRNA
EMBL
BC007628; AAH07628.1
; -; mRNA
EMBL
BC010409; AAH10409.3
; -; mRNA
EMBL
BC067744; AAH67744.2
; -; mRNA
EMBL
BC084574; AAH84574.2
; -; mRNA
EMBL
AB045973; BAB40770.1
; -; Genomic_DNA
EMBL
AB041267; BAA94607.1
; -; mRNA
CCDS
CCDS11399.1; -
; .
PIR
A31370; KRHU9
; .
RefSeq
NP_002267.2; NM_002276.4
; .
UniGene
Hs.654568; -
; .
ProteinModelPortal
P08727; -
; .
SMR
P08727; -
; .
BioGrid
110078; 50
; .
DIP
DIP-35655N; -
; .
IntAct
P08727; 78
; .
MINT
MINT-1438883; -
; .
STRING
9606.ENSP00000355124; -
; .
iPTMnet
P08727; -
; .
PhosphoSitePlus
P08727; -
; .
SwissPalm
P08727; -
; .
BioMuta
KRT19; -
; .
DMDM
311033484; -
; .
SWISS-2DPAGE
P08727; -
; .
EPD
P08727; -
; .
MaxQB
P08727; -
; .
PaxDb
P08727; -
; .
PeptideAtlas
P08727; -
; .
PRIDE
P08727; -
; .
DNASU
3880; -
; .
Ensembl
ENST00000361566; ENSP00000355124
; ENSG00000171345; .
GeneID
3880; -
; .
KEGG
hsa:3880; -
; .
UCSC
uc002hxd.5; human
; .
CTD
3880; -
; .
DisGeNET
3880; -
; .
GeneCards
KRT19; -
; .
HGNC
HGNC:6436; KRT19
; .
HPA
CAB000031; -
; .
HPA
HPA002465; -
; .
MIM
148020; gene
; .
neXtProt
NX_P08727; -
; .
OpenTargets
ENSG00000171345; -
; .
PharmGKB
PA30225; -
; .
eggNOG
ENOG410IFTF; Eukaryota
; .
eggNOG
ENOG410Y9IV; LUCA
; .
GeneTree
ENSGT00760000118808; -
; .
HOVERGEN
HBG013015; -
; .
InParanoid
P08727; -
; .
KO
K07604; -
; .
OMA
DAHYNNL; -
; .
OrthoDB
EOG091G087I; -
; .
PhylomeDB
P08727; -
; .
TreeFam
TF332742; -
; .
Reactome
R-HSA-6805567; Keratinization
; .
Reactome
R-HSA-6809371; Formation of the cornified envelope
; .
SIGNOR
P08727; -
; .
ChiTaRS
KRT19; human
; .
GeneWiki
Keratin_19; -
; .
GenomeRNAi
3880; -
; .
PRO
PR:P08727; -
; .
Proteomes
UP000005640; Chromosome 17
; .
Bgee
ENSG00000171345; -
; .
ExpressionAtlas
P08727; baseline and differential
; .
Genevisible
P08727; HS
; .
GO
GO:0016327; C:apicolateral plasma membrane
; IEA:Ensembl; .
GO
GO:0071944; C:cell periphery
; IDA:MGI; .
GO
GO:0043034; C:costamere
; IDA:UniProtKB; .
GO
GO:0005829; C:cytosol
; TAS:Reactome; .
GO
GO:0016010; C:dystrophin-associated glycoprotein complex
; IEA:Ensembl; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0005882; C:intermediate filament
; TAS:ProtInc; .
GO
GO:0005886; C:plasma membrane
; IDA:CACAO; .
GO
GO:0042383; C:sarcolemma
; IEA:Ensembl; .
GO
GO:1990357; C:terminal web
; IEA:Ensembl; .
GO
GO:0030018; C:Z disc
; IEA:Ensembl; .
GO
GO:0005200; F:structural constituent of cytoskeleton
; TAS:ProtInc; .
GO
GO:0008307; F:structural constituent of muscle
; IDA:UniProtKB; .
GO
GO:0060706; P:cell differentiation involved in embryonic placenta development
; IEA:Ensembl; .
GO
GO:0070268; P:cornification
; TAS:Reactome; .
GO
GO:0031424; P:keratinization
; TAS:Reactome; .
GO
GO:0007219; P:Notch signaling pathway
; IEA:Ensembl; .
GO
GO:0043627; P:response to estrogen
; IEP:UniProtKB; .
GO
GO:0045214; P:sarcomere organization
; IDA:UniProtKB; .
GO
GO:0016032; P:viral process
; IEA:UniProtKB-KW; .
InterPro
IPR001664; IF
; .
InterPro
IPR018039; Intermediate_filament_CS
; .
InterPro
IPR002957; Keratin_I
; .
InterPro
IPR009053; Prefoldin
; .
PANTHER
PTHR23239; PTHR23239
; 1; .
Pfam
PF00038; Filament
; 1; .
PRINTS
PR01248; TYPE1KERATIN
; .
SMART
SM01391; Filament
; 1; .
SUPFAM
SSF46579; SSF46579
; 1; .
PROSITE
PS00226; IF
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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